John C. Malone Professor of Biomedical Engineering, Computer Science, Radiology And Neurosurgery

Research Interests

• Medical imaging
• Computed tomography (CT) and cone-beam CT
• Multi-modality image registration
• Image-guided surgery
• Patient safety

Dr. Siewerdsen leads a program for translational research in medical imaging and image-guided interventions at Johns Hopkins University. Primary research interests include the development of new imaging technologies, 3D imaging methods, and image registration, with a focus on CT and cone-beam CT combined with other modalities for improved diagnostic accuracy and high-precision intervention. Collaborations and areas of major clinical interest include Neurosurgery, Orthopaedic Surgery, Otolaryngology, Radiation Oncology, Interventional Radiology, and Diagnostic Radiology. His work includes early development of flat-panel x-ray detectors and pioneering work in cone-beam CT, including intraoperative C-arms, dedicated cone-beam CT systems for radiology, and the first cone-beam CT system for image-guided radiation therapy, now standard of care. He worked previously at William Beaumont Hospital Research Institute (Royal Oak MI) and the Ontario Cancer Institute / University of Toronto (Toronto ON) after receiving his PhD in Physics from the University of Michigan in 1998.