The Cardiac Surgery Division at the Johns Hopkins Hospital is a highly complex organization that involves multi-disciplinary services and care teams. The Cardiac Surgery team is routinely monitoring their quality of care, forming and testing hypotheses as to which parts of the care system need to be more efficient. This Malone- funded project establishes the foundation to investigate and pinpoint inefficiencies in cardiac surgery care by analyzing comprehensive data sets taken from a large cohort of patients. Researchers and clinicians from the Malone Center and Cardiac Surgery team up to validate and investigate four potential inefficiencies in the Cardiac Surgery care system: (1) Prediction of length of stay, (2) Early diagnosis of Heparin Induced Thrombocytopenia (HIT), (3) Measuring deviation from routine daily pathways, and (4) Prediction of Bounce-back patients to ICU. The larger goal of the project is to explore new data-driven approaches to improve the quality and efficiency of care for cardiac surgery patients.